VU6007477

Overview

VU6007477 is a brain-penetrant, selective M1 positive allosteric modulator ( PAM ) with an EC 50 value of 230 nM. VU6007477 is also a human P-glycoprotein ( P-gp ) substrate with moderate permeability. VU6007477 displays improved central nervous system (CNS) penetration over the hydroxylated congeners. VU6007477 a pyranyl amide derivative, which is promising for research of robust cholinergic seizure activity.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > P-glycoprotein

Product Information

• Catalog No.: HY-123934
• CAS No.: 2220141-46-6
• Molecular Formula: C24H26N6O2
• Molecular Weight: 430.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source