3,4-Dephostatin

Overview

3,4-Dephostatin (Methyl-3,4-dephostatin) is an inhibitor of protein-tyrosine phosphatase ( PTPase ). 3,4-Dephostatin accelerates nerve growth factor (NGF)-induced neurite formation in PC12h cells. 3,4-Dephostatin sustains the NGF-induced tyrosine phosphorylation of proteins, most prominently that of mitogen-activated protein ( MAP ) kinase. 3,4-Dephostatin also prolongs epidermal growth factor ( EGF )-induced tyrosine phosphorylation and activation of MAP kinase.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > MAP3K | Products > Signaling Pathways > MAP4K | Products > Signaling Pathways > Phosphatase

Product Information

• Catalog No.: HY-124152
• CAS No.: 173043-84-0
• Molecular Formula: C7H8N2O3
• Molecular Weight: 168.15
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source