TGX-115 is a p110β/p110δ-selective, PI3-K inhibitor. TGX-115 blocks p110β-mediated Akt phosphorylation induced by lysophosphatidic acid (LPA) in L6 myotubes, reduces insulin-stimulated PI(3,4)P2 and PIP3 levels in 3T3-L1 adipocytes. TGX-115 can be used for the study of diabetes mellitus.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > PI3K
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