Duocarmycin SA

Overview

Duocarmycin SA is an orally active antitumor antibiotic with an IC 50 of 10 pM. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro.

Application

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Product Information

• Catalog No.: HY-12456
• CAS No.: 130288-24-3
• Molecular Formula: C25H23N3O7
• Molecular Weight: 477.47
• Purity: 99.89%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (5.24 mM); Clear solution
• Availability: In-stock

Source

Original product source