ML279 is a potent scavenger receptor, class B, type I ( SR-BI ) inhibitor. ML279 can inhibit SR-BI-mediated lipid uptake by stabilizing the binding of HDL to SR-BI ( EC 50 = 0.27 μM). ML279 can be used for the researches of infection and cardiovascular disease , such as atherosclerosis and HCV infection .
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