CCR1 antagonist 12

Overview

CCR1 antagonist 12 (Compound 12) is an antagonist for CCR1 with IC 50 of 3 nM for human CCR1 . CCR1 antagonist 12 inhibits CCL3-induced transwell chemotaxis with an IC 50 of 0.009 µM. CCR1 antagonist 12 exhibits good pharmacokinetic characters in rats model.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > CCR

Product Information

• Catalog No.: HY-124668
• CAS No.: 921208-19-7
• Molecular Formula: C25H27ClFN3O4
• Molecular Weight: 487.95
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source