ISRIB (trans-isomer)

Overview

ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC 50 of 5 nM. ISRIB potently reverses the effects of eIF2α phosphorylation (IC 50 =5 nM).

Application

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Product Information

• Catalog No.: HY-12495
• CAS No.: 1597403-47-8
• Molecular Formula: C22H24Cl2N2O4
• Molecular Weight: 451.34
• Purity: 99.49%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: 0.83 mg/mL (1.84 mM); Suspended solution; Need ultrasonic and warming and heat to 60°C
• Availability: In-stock

Source

Original product source