GV-58

Overview

GV-58 is a novel N- and P/Q-type calcium ( Ca 2+ ) channel agonist with EC 50 s of 7.21 and 8.81 μM, respectively. GV-58 slows the deactivation of channels, resulting in a large increase in presynaptic Ca 2+ entry during activity. GV-58 can be used in lambert-eaton myasthenic syndrome (LEMS) research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Calcium Channel

Product Information

• Catalog No.: HY-12498
• CAS No.: 1402821-41-3
• Molecular Formula: C18H26N6OS
• Molecular Weight: 374.50
• Purity: 99.22%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.68 mM); Clear solution
• Availability: In-stock

Source

Original product source