ETX0282

Overview

ETX0282 is an orally active prodrug, with its active form being ETX1317. ETX0282 and ETX1317 are β-lactamase inhibitors of the dioxolane-dibenzo-p-heptane (DBO) type. ETX0282 exhibits high stability during intestinal absorption and can be efficiently converted into ETX1317 in the liver. ETX0282 alone has no bactericidal activity, but in a mouse model of neutropenic thigh infection , it can significantly reduce bacterial load when used in combination with Cefpodoxime Proxetil ( HY-N7101 ). ETX0282 can be used for the study of infections caused by drug-resistant Gram-negative bacteria.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Beta-lactamase

Product Information

• Catalog No.: HY-125356
• CAS No.: 2209871-83-8
• Molecular Formula: C13H18FN3O5
• Molecular Weight: 315.30
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source