Dantrolene sodium hemiheptahydrate

Overview

Dantrolene sodium hemiheptahydrate is an orally active, non-competitive glutathione reductase inhibitor with a K i of 111.6 μM and an IC 50 of 52.3 μM. Dantrolene sodium hemiheptahydrate is also a calcium channel protein inhibitor. Dantrolene sodium hemiheptahydrate inhibits the release of Ca 2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene sodium hemiheptahydrate offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties.

Application

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Product Information

• Catalog No.: HY-12542A
• CAS No.: 24868-20-0
• Molecular Formula: C14H16N4NaO8.5
• Molecular Weight: 399.31
• Purity: 99.79%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 0.5 mg/mL (1.25 mM); Clear solution
• Availability: In-stock

Source

Original product source