L 705589

Overview

L-705589 is a semi-synthetic penicillin-type antifungal agent. L-705589 exerts its antifungal effect by inhibiting the 1,3-β-D-glucan synthase in the fungal cell wall. L-705589 exhibits potent bactericidal activity against various Candida species (such as Candida albicans , Candida glabrata , Candida krusei , etc.) (MFC: 0.06 - 8 μg/mL), but has relatively weak activity against Cryptococcus neoformans (MFC: 32 - 64 μg/mL). L-705589 remains active against drug-resistant Candida strains and is not prone to inducing drug resistance. L-705589 significantly improves survival rates in the model of minor invasive aspergillosis.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Fungal Infection | Products > Disease Areas > Candida Infection | Products > Disease Areas > Aspergillus Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Fungal

Product Information

• Catalog No.: HY-125459
• CAS No.: 150220-81-8
• Molecular Formula: C52H85N9O17
• Molecular Weight: 1108.28
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source