Rivipansel

Overview

Rivipansel is a small-molecule glycomimetic pan-selectin antagonist with inhibitory activity against E-selectin and P-selectin . Rivipansel binds tightly to the lectin domain of E-selectin , and selectively blocks the recognition of CD62L by E-selectin without affecting the binding of PSGL-1 to E-selectin . Rivipansel functionally inhibits the adhesion of hematopoietic cells to endothelial cells, and is applicable to research related to sickle cell disease.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Blood Disease | Products > Disease Areas > Sickle Cell Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > E-Selectin

Product Information

• Catalog No.: HY-125475
• CAS No.: 927881-99-0
• Molecular Formula: C58H74N6O31S3
• Molecular Weight: 1447.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source