TOP1362 is a narrow spectrum kinase inhibitor. TOP1362 is a potent inhibitor of P38-α and Syk kinases with K d values of 26 and 18 nM, respectively and an IC 50 of 14 nM in the Src kinase activity assay. TOP1362 potently inhibits P38-α, Src and Syk . TOP1362 can be used in the research of dry eye syndrome.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Visual System Disease | Products > Disease Areas > Dry Eye Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > Syk | Products > Signaling Pathways > Src
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