(S)-PNU-282987 hydrochloride

(S)-PNU-282987 hydrochloride
  • CAS No.:128311-08-0
  • Grade:99.98%
  • Formula:C14H18Cl2N2O
  • M.W.:301.21

Overview

(S)-PNU-282987 hydrochloride is an isoform of PNU-282987 ( HY-12560 ). PNU-282987 (free base) is a potent α7 nicotinic acetylcholine receptor ( nAChR ) agonist with an EC 50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT 3 receptor with an IC 50 of 4541 nM. PNU-282987 (free base) can be used for the research of central and peripheral nervous systems.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > nAChR | Products > Signaling Pathways > 5-HT Receptor

Product Information

  • Catalog No.: HY-12560C
  • CAS No.: 128311-08-0
  • Molecular Formula: C14H18Cl2N2O
  • Molecular Weight: 301.21
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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