Viloxazine hydrochloride

Overview

Viloxazine hydrochloride is a non-brain-penetrant, selective norepinephrine transporter (NET) inhibitor ( IC 50 =0.26 μM) and 5-HT receptor modulator. Viloxazine antagonizes 5-HT2B receptors ( K i =4.2 μM) and agonizes 5-HT2C receptors ( EC 50 =32 μM), respectively, and enhances 5-HT neurotransmission by modulating 5-HT2B/C receptors. Viloxazine also competitively inhibits NET from increasing NE and DA levels in the synaptic cleft, and can be used in the study of attention deficit hyperactivity disorder (ADHD).

Application

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Product Information

• Catalog No.: HY-125784
• CAS No.: 35604-67-2
• Molecular Formula: C13H20ClNO3
• Molecular Weight: 273.76
• Purity: 98.94%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source