(S,R,S)-MI-1061

Overview

(S,R,S)-MI-1061 is the isomer of MI-1061 ( HY-125858 ). (S,R,S)-MI-1061 can used to synthesize Antibody-Drug Conjugates (ADCs) . MI-1061 is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor ( IC 50 =4.4 nM; K i =0.16 nM). MI-1061 potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity.

Application

Products | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Others | Products > Signaling Pathways > Drug-Linker Conjugates for ADC | Products > Signaling Pathways > MDM-2/p53

Product Information

• Catalog No.: HY-125858B
• CAS No.: 1410738-90-7
• Molecular Formula: C30H26Cl2FN3O4
• Molecular Weight: 582.45
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source