CB10-277 is a Dacarbazine ( HY-B0078 ) analog that mediates alkylation of guanine residues at the O 6 position in DNA and subsequently reduces ATase levels in lymphocytes and tumors. CB10-277 is useful in the study of metastatic malignant melanoma.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Nucleoside Antimetabolite/Analog | Products > Signaling Pathways > DNA Alkylator/Crosslinker
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