SBI-797812

Overview

SBI-797812 is an orally active nicotinamide phosphoribosyltransferase ( NAMPT ) activator. SBI-797812 shifts NAMPT to NMN formation, increases NAMPT affinity for ATP, stabilizes phosphorylated NAMPT , promotes consumption of the pyrophosphate by-product, and blunts feedback inhibition by NAD + . SBI-797812 increases intracellular nicotinamide mononucleotide (NMN) and elevates liver NAD + in mice.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > NAMPT

Product Information

• Catalog No.: HY-126255
• CAS No.: 2237268-08-3
• Molecular Formula: C19H22N4O4S
• Molecular Weight: 402.47
• Purity: 99.88%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2.08 mg/mL (5.17 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source