NRL-1049 dihydrochloride

Overview

NRL-1049 dihydrochloride (BA-1049) is a selective and orally active rho-associated protein kinase 2 ( ROCK2 ) inhibitor with an IC 50 of 0.59 μM. NRL-1049 dihydrochloride shows selectivity for ROCK2 is 44 times that of ROCK1 ( IC 50 = 26 μM). NRL-1049 dihydrochloride can preserve the blood-brain barrier after acute injury.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > ROCK

Product Information

• Catalog No.: HY-126432
• CAS No.: 1973494-17-5
• Molecular Formula: C16H23Cl2N3O2S
• Molecular Weight: 392.34
• Purity: 99.20%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source