LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC 50 value of 0.13 nM. LDC4297 hydrochloride inhibits human cytomegalovirus (HCMV) replication with an EC 50 value of 24.5 nM. LDC4297 hydrochloride shows broad antiviral activities to Herpesviridae , Adenoviridae , Poxviridae , Retroviridae and Orthomyxoviridae with EC 50 values of 0.02-1.21 μM. LDC4297 hydrochloride can be used for the research of infection .
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