Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis . Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC 50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC 50 is 0.99, 0.51 and 1.4 µg/mL, respectively.
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