Tedisamil dihydrochloride

Overview

Tedisamil (KC-8857) dihydrochloride is an antiarrhythmic compound with important biological activities. Tedisamil dihydrochloride exhibits a significant slowing effect on heart rate, which is achieved by inhibiting the transient outward potassium current (I(to)) in the atrium. Tedisamil dihydrochloride inhibits multiple potassium currents, including IK, K(ATP), and PKA-activated chloride channels, thereby prolonging the cardiac action potential and QT interval, and increasing cardiac reentry. Tedisamil dihydrochloride has antiarrhythmic effects on ventricular arrhythmias and atrial flutter in animal models.

Application

Products | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-126704A
• CAS No.: 132523-84-3
• Molecular Formula: C19H34Cl2N2
• Molecular Weight: 361.39
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source