Entrectinib (Standard)

Overview

Entrectinib (Standard) is the analytical standard of Entrectinib. This product is intended for research and analytical applications. Entrectinib (NMS-E628) is an orally active, BBB-penetrated and centrally active inhibitor of TrkA/B/C , ROS1 and ALK , with IC 50 values of 1, 3, 5, 12 and 7 nM, respectively. Entrectinib induces apoptosis and cycle arrest in cancer cells, has antitumor activity, and attenuates bleomycin-induced lung fibrosis in mice.

Application

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Product Information

• Catalog No.: HY-12678R
• CAS No.: 1108743-60-7
• Molecular Formula: C31H34F2N6O2
• Molecular Weight: 560.64
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source