Diclofenac acyl glucuronide

Overview

Diclofenac acyl glucuronide (D-1-O-G) is an orally active glucuronide metabolite of Diclofenac ( HY-15036 ). Diclofenac acyl glucuronide exhibits SOD inhibitory activity, COX-1 inhibitory activity ( IC 50 = 0.620 μM), and COX-2 inhibitory activity ( IC 50 = 2.91 μM). Diclofenac acyl glucuronide induces reactive oxygen species ( ROS ) production and acts as a substrate of OATP2B1 . Diclofenac acyl glucuronide induces small intestinal ulcers . Diclofenac acyl glucuronide can be used in research related to intestinal diseases and small intestinal ulcers.

Application

Products | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Peptic Ulcer Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > OAT | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > SOD | Products > Signaling Pathways > COX | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

• Catalog No.: HY-126848
• CAS No.: 64118-81-6
• Molecular Formula: C20H19Cl2NO8
• Molecular Weight: 472.27
• Purity: 98.34%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source