NGB 2904

Overview

NGB 2904 is a potent, selective, orally active and brain-penetrated antagonist of dopamine D3 receptor , with a K i of 1.4 nM. NGB 2904 shows selectivity for D3 over D2, 5-HT2, α1, D4, D1 and D5 receptors (K i s=217, 223, 642, >5000, >10000 and >10000 nM, respectively). NGB 2904 antagonizes Quinpirole-stimulated mitogenesis.

Application

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Product Information

• Catalog No.: HY-12697
• CAS No.: 189060-98-8
• Molecular Formula: C28H29Cl2N3O
• Molecular Weight: 494.46
• Purity: 99.76%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: 5 mg/mL (10.11 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source