Amicoumacin A is an orally active antibiotic . Amicoumacin A targets bacterial ribosomes and inhibits bacterial translation by stabilizing the interaction between mRNA and ribosomes. Amicoumacin A induces cancer cell death by targeting eukaryotic ribosomes. Amicoumacin A exhibits anti-inflammatory and anti-ulcer activities, inhibits carrageenan-induced paw edema, and prevents stress-induced gastric ulcers. Amicoumacin A inhibits the growth of Gram-positive bacteria, Salmonella spp., Shigella spp., Helicobacter pylori , and methicillin-resistant Staphylococcus aureus . Amicoumacin A can be used in the research of lung cancer , breast cancer , bacterial infections, inflammatory edema and gastric ulcers [2] .
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