Platensimycin

Overview

Platensimycin is an antibiotic produced by S. platensis that inhibits gram-positive bacteria by selectively inhibiting cellular lipid biosynthesis ( IC 50 =0.1 μM). Platensimycin targets the β-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids ( IC 50 s=48 nM and 160 nM for S.aureus and E.coli enzymes , respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-127146
• CAS No.: 835876-32-9
• Molecular Formula: C24H27NO7
• Molecular Weight: 441.47
• Purity: 95.1%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source