BRL-44408 maleate

Overview

BRL-44408 maleate is a selective, blood-brain barrier-permeable α 2 A-adrenergic receptor antagonist with a K i value of 8.56 nM against human targets. BRL-44408 maleate exhibits activities such as antidepressant, analgesic effects and attenuation of sepsis-induced acute lung injury by regulating the release of neurotransmitters such as norepinephrine and dopamine, or inhibiting signaling pathways including ERK1/2 , p38MAPK and p65 . BRL-44408 maleate can be used in studies related to acute respiratory distress syndrome, depression and visceral pain.

Application

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Product Information

• Catalog No.: HY-12716A
• CAS No.: 681806-46-2
• Molecular Formula: C17H21N3O4
• Molecular Weight: 331.37
• Purity: 99.0%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source