SCH 50911 hydrochloride

Overview

SCH 50911 dihydrochloride is a selective, orally active, blood-brain barrier permeable GABA-B receptor ( GABA-B Receptor ) antagonist with an IC 50 of 1.1 μM in rats. SCH 50911 dihydrochloride blocks baclofen-induced antitussive effects, regulates neuronal firing and GABA release. SCH 50911 dihydrochloride promotes spontaneous seizures during withdrawal in ethanol-dependent rats, alters reward-related neurotransmission, and reduces or suppresses lever responding and self-administration behaviors of alcohol and sucrose in rats. SCH 50911 dihydrochloride is applicable to research related to ethanol withdrawal syndrome, absence epilepsy and alcohol use disorder.

Application

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Product Information

• Catalog No.: HY-12783
• CAS No.: 160415-07-6
• Molecular Formula: C8H16ClNO3
• Molecular Weight: 209.67
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source