VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M 4 ) positive allosteric modulator (PAM), with EC 50 s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M 4 , respectively. Used in the research of neuropsychiatric disorders.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mAChR
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