CB-5083

Overview

CB-5083 is a first-in-class, potent, selective, and orally bioavailable inhibitor of the p97 AAA ATPase / VCP . CB-5083 selectively inhibits p97 through its D2 site with the IC 50 of 11 nM.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > p97

Product Information

• Catalog No.: HY-12861
• CAS No.: 1542705-92-9
• Molecular Formula: C24H23N5O2
• Molecular Weight: 413.47
• Purity: 99.90%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.05 mM); Clear solution
• Availability: In-stock

Source

Original product source