2'-Fluorothymidine

Overview

2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine) is a nucleoside analog and hCNT inhibitor, with an IC 50 of 1.1 μM against hCNT1 and an IC 50 of 9.7 μM against hCNT3 . 2'-Fluorothymidine undergoes phosphorylation by cytosolic thymidine kinase (TK1) and mitochondrial thymidine kinase (TK2). 2'-Fluorothymidine acts as a backbone stabilizer in oligonucleotide synthesis and can also form radiolabeled candidates. 2'-Fluorothymidine is applicable in tumor-related research.

Application

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Product Information

• Catalog No.: HY-128710
• CAS No.: 122799-38-6
• Molecular Formula: C10H13FN2O5
• Molecular Weight: 260.22
• Purity: 99.07%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source