Ifenprodil

Overview

Ifenprodil (NP-120), a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil exerts high affinity at NR1A/NR2B receptors ( IC 50 =0.34 μM) over 400-fold than at NR1A/NR2A receptors ( IC 50 =146 μM). Ifenprodil is an α1 adrenergic receptor antagonist. Ifenprodil inhibits GIRK (Kir3) , reduces inward currents through the basal GIRK activity. Ifenprodil has reliable inhibitory effects against A/H1N1 strains (EC 50 of 6.6 µM). Ifenprodil has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease.

Application

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Product Information

• Catalog No.: HY-12882
• CAS No.: 23210-56-2
• Molecular Formula: C21H27NO2
• Molecular Weight: 325.44
• Purity: 99.94%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1.25 mg/mL (3.84 mM); Clear solution
• Availability: In-stock

Source

Original product source