Duocarmycin DM free base

Overview

Duocarmycin DM free base, a DNA minor-groove alkylator , is an antibody agent conjugates (ADCs) toxin. Duocarmycin DM free base is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA Alkylator/Crosslinker | Products > Signaling Pathways > ADC Payloads

Product Information

• Catalog No.: HY-128915
• CAS No.: 1116745-06-2
• Molecular Formula: C26H26ClN3O3
• Molecular Weight: 463.96
• Purity: 99.69%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2 mg/mL (4.31 mM); Clear solution
• Availability: In-stock

Source

Original product source