CL2 Linker is a cleavable ADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in agent substitution (~6), cell binding (K d ~1.2 nM), cytotoxicity (IC 50 ~2.2 nM), and serum stability in vitro (t 1/2 ~20 hours).
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > ADC Linkers
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