(-)-MDO-NPA is an N-propylnorapomorphine analog and a D1R/D2R dual-target ligand. (-)-MDO-NPA has EC 50 values of 1949 nM ( D1R ) and 520 nM ( D2R ) for β-arrestin . (-)-MDO-NPA has EC 50 values of 717.5 nM ( D1R ) and 7.7 nM ( D2R ) for cAMP . (-)-MDO-NPA can be used in the research of dopamine-related diseases such as Parkinson’s disease.
Products | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Receptor
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