Doxapram (hydrochloride) is a ventilatory stimulant. Doxapram (hydrochloride) inhibits TASK Tandem Pore (K 2P ) potassium channel function. Doxapram (hydrochloride) inhibits TASK-1 and TASK-3 with an EC 50 values of 410 and 37 nM, respectively. Doxapram (hydrochloride) inhibits TASK-1/TASK-3 heterodimeric channel function with an EC 50 value of 9 μM. Doxapram (hydrochloride) can be studied in research on apnea in preterm infants.
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