AMG-8718

Overview

AMG-8718 is a potent, selective and orally active BACE1 inhibitor with IC 50 values of 0.0007, 0.005 µM for BACE1 and BACE2 , respectively. AMG-8718 significantly decreases Aβ 40 levels in the CSF and brain.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Beta-secretase

Product Information

• Catalog No.: HY-12938
• CAS No.: 1215868-94-2
• Molecular Formula: C25H19FN4O3
• Molecular Weight: 442.44
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source