RO4583298

Overview

RO4583298 is a potent, orally active dual antagonist of NK 1 (human and gerbil)/ NK 3 (human, cynomolgus monkey, gerbil and guinea-pig). RO4583298 inhibits senktide-induced potentiation of spontaneous activity of dopaminergic neurons. RO4583298 can block gerbil foot tapping response and inhibits mouse tail whips.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Neurokinin Receptor

Product Information

• Catalog No.: HY-129448
• CAS No.: 825643-56-9
• Molecular Formula: C30H30F7N3O3
• Molecular Weight: 613.57
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source