L-Canaline is a nonprotein amino acid stored in many leguminous plants . L-Canaline is a cytotoxic metabolite catalyzed by L-canavanine and its arginase . L-Canaline is a potent and irreversible inhibitor of ornithine aminotransferase . L-Canaline inhibits the growth of the malaria parasite Plasmodium falciparum with an IC 50 of 297 nM. L-Canaline has anticancer and antiproliferative effects.
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