(E/Z)-CLH304a

Overview

(E/Z)-CLH304a (GABAB receptor antagonist 1) is a mixture of (E)-CLH304a and (Z)-CLH304a. (E)-CLH304a (CLH304a; HY-129636) is a specific and noncompetitive GABA B receptor negative allosteric modulator (NAM). CLH304a inhibits Baclofen ( HY-B0007 )-induced ERK1/2 phosphorylation in HEK293 cells overexpressing GABAB receptors.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GABA Receptor | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-129636A
• CAS No.: 797-17-1
• Molecular Formula: C18H24O4
• Molecular Weight: 304.38
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Solubility: ≥ 5 mg/mL (16.43 mM); Clear solution

Source

Original product source