LY127210 free base is an orally active peripheral arterial vasodilating antihypertensive agent. LY127210 free base interferes with the baroreflex mechanism, exerts direct myocardial bradycardic activity, has no α or β receptor blocking properties, and acts via all conventional administration routes. LY127210 free base reduces vascular resistance, cardiac output, heart rate, left ventricular end-diastolic pressure, regional vascular resistance, as well as blood flow in the skin and cerebral cortex. LY127210 free base can be used in research related to hypertension.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Hypertension | Products > Research Areas > Cardiovascular Disease
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