AMG 837 hemicalcium is a potent, orally bioavailable and partial agonist of GPR40/FFA1 . AMG 837 hemicalcium inhibits specific [ 3 H]AMG 837 binding at the human FFA1 receptor with a pIC 50 of 8.13. AMG 837 hemicalcium could enhance insulin secretion and lower glucose levels in rodents.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Free Fatty Acid Receptor
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