Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp . Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H + -ATPases (V-ATPases) . Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi . Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC).
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