Reverse transcriptase-IN-1

Overview

Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. Reverse transcriptase-IN-1 has antiviral activity with EC 50 values of 3.4 nM, 4.3 nM and 3.6 nM for HIV-1 III B , E138K and K103N mutants, respectively. Reverse transcriptase-IN-1 also has an IC 50 of 13.7 nM against HIV-1 reverse transcriptase enzyme .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > HIV

Product Information

• Catalog No.: HY-130241
• CAS No.: 2380001-43-2
• Molecular Formula: C25H17N7O2
• Molecular Weight: 447.45
• Purity: 98.99%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (2.79 mM); Clear solution
• Availability: In-stock

Source

Original product source