LC3-mHTT-IN-AN2

Overview

LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Atg8/LC3 | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-130259
• CAS No.: 7758-73-8
• Molecular Formula: C15H10O4
• Molecular Weight: 254.24
• Purity: 98.87%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (8.18 mM); Clear solution
• Availability: In-stock

Source

Original product source