PROTAC BCR-ABL1 ligand 1

PROTAC BCR-ABL1 ligand 1
  • CAS No.:2489876-34-6
  • Grade:99.17%
  • Formula:C17H12F3N3O2
  • M.W.:347.29

Overview

PROTAC BCR-ABL1 ligand 1, compound GMB-475, is the ligand of PROTAC that allosterically targets BCR-ABL1 protein and recruits the E3 ligase Von Hippel-Lindau, resulting in ubiquitination and subsequent degradation of BCR-ABL1.

Application

Products | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Bcr-Abl | Products > Signaling Pathways > Ligands for Target Protein for PROTAC

Product Information

  • Catalog No.: HY-130297
  • CAS No.: 2489876-34-6
  • Molecular Formula: C17H12F3N3O2
  • Molecular Weight: 347.29
  • Purity: 99.17%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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