(+)-JQ-1

Overview

(+)-JQ-1 (JQ1), a chemical probe, is a potent, specific, CNS-penetrant and reversible BET bromodomain inhibitor, with IC 50 s of 77 and 33 nM for the first and second bromodomain ( BRD4(1/2) ). (+)-JQ-1 also activates autophagy .

Application

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Product Information

• Catalog No.: HY-13030
• CAS No.: 1268524-70-4
• Molecular Formula: C23H25ClN4O2S
• Molecular Weight: 456.99
• Purity: 99.91%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 2.5 mg/mL (5.47 mM); Clear solution
• Availability: In-stock

Source

Original product source