Fostamatinib disodium hexahydrate

Fostamatinib disodium hexahydrate
  • CAS No.:914295-16-2
  • Grade:99.46%
  • Formula:C23H36FN6Na2O15P
  • M.W.:732.51
  • Solvent:8.33 mg/mL (11.37 mM); Suspended solution; Need ultrasonic

Overview

Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a K i of 30 nM and an IC 50 of 41 nM. R406 also inhibits Lyn (IC 50 =63 nM) and Lck (IC 50 =37 nM).

Application

Products | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Arthritis | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Viral Infection | Products > Disease Areas > SARS-CoV-2 Infection | Products > Disease Areas > Rheumatoid Arthritis | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Syk | Products > Signaling Pathways > FLT3

Product Information

  • Catalog No.: HY-13038B
  • CAS No.: 914295-16-2
  • Molecular Formula: C23H36FN6Na2O15P
  • Molecular Weight: 732.51
  • Purity: 99.46%
  • Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
  • Solubility: 8.33 mg/mL (11.37 mM); Suspended solution; Need ultrasonic
  • Availability: In-stock

Source

Original product source


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