PROTAC EED degrader-2

Overview

PROTAC EED degrader-2 is a von Hippel-Lindau -based PROTAC targeting EED with a pK D of 9.27. PROTAC EED degrader-2 is a polycomb repressive complex 2 ( PRC2 ) inhibitor ( pIC 50 =8.11) targeting the EED subunit. (Pink: EED ligand ( HY-130815 ); Blue: VHL ligand ( HY-125845 ); Black: linker ( HY-W014099 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Histone Methyltransferase

Product Information

• Catalog No.: HY-130615
• CAS No.: 2639882-69-0
• Molecular Formula: C50H58FN11O6S
• Molecular Weight: 960.13
• Purity: 99.90%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2 mg/mL (2.08 mM); Clear solution
• Availability: In-stock

Source

Original product source